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E-Health: Low Cost Sensors for Early Detection of Childhood DiseaseFebruary 20, 2014

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From Libelium, we bring you a very interesting article about early detection of pneumonia in children.

Pneumonia is the number 1 killer of children worldwide with 2 million deaths each year. With a child dying every 20 seconds, pneumonia is a significant contributor to neonatal mortality in developing countries – more than AIDS, malaria and measles combined.

The illness is treatable and preventable, but accurate early detection is key.

To reduce child mortality due to Acute Respiratory Infection (ARI), the Smart Object Sensing Array invented by Guardit and licensed by Inspire Living Inc., contracted with the global NGO Project HOPE to create a device to aid in the efficient detection of tachypnea, an indication of pneumonia in children, based on Libelium’s e-Health Sensor Platform.

Inspire Living developed an Infant Respiratory Rate Sensor device (Inspire™) from pioneering work in smart object sensing and object pattern recognition. Designed for use by community health workers who must accurately determine respiratory rates in children as part of diagnosing pneumonia, INSPIRE is an automated electronic device that satisfies UNICEF’s specifications for global products.

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An Affordable Prototyping Platform for e-Health

Creating new healthcare applications or medical devices requires access to prototyping platforms that were once very costly to obtain, limiting development to research labs or well-funded corporations. “One of the challenges to e-Health innovation has been the lack of affordable sensors. You had to make a huge investment even before knowing if your project was viable. That is why we developed the e-Health Sensor Platform”, said Alicia Asín, CEO and co-founder of Libelium. “When you see all that can be achieved with an inexpensive prototyping platform like ours, it makes it worthwhile for makers to change things.”

Inspire Living built the INSPIRE prototypes using Libelium’s e-Health Sensor hardware platform. “Libelium knocked it out of the ball park with their e-Health Sensor Platform Kit. With this, we had available the core of what we needed so we could add our value and focus on our solution. Libelium developed the foundation in software for us to build on; they had the hardware compatibility and conformity so that others could understand and reference our solution, and accept our design decisions more easily”, said Michael Script, co-founder of Inspire Living. “I would sum up the impact of working with using the products, services, support and forums from Libelium as game-changing.”

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The e-Health Sensor Platform with its array of sensors, electronics
and software APIs

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e-Health Sensor Board top view

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After years of development and hundreds of iterations, Inspire Living, an innovations company specialized in smart object sensing with portable notification, was close to launching a new sensor system for counting breath rate for use in developing countries. They had patented a sensor and sourced a special material that could adhere to a child’s skin to keep the device in place. They had created easy-to-read icons to start the device and display the number of breaths counted; they had devised a way to manually charge the device for autonomy, for use in places where batteries and sunlight were scarce. At last ready to show the device to the world, they set out to demonstrate it to the World Health Organization (WHO), UNICEF, USAID, Project HOPE, and the Gates Foundation.

Accuracy in breath rate testing

In developing countries, aid workers and medical professionals use counting beads and stopwatches to test breath rate: this can lead to misdiagnosis by either under-counting or over-counting. A moving child, difficulties in remembering the count, or distractions during the count are all factors cited by UNICEF as major impediments to accurate respiratory rate counts.

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e-Health Sensor Kit: a medical monitoring platform combines 10 different sensor operations

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Script, an inventor with a long career, found that Libelium had developed an e-Health sensor board integrating a number of different health tests performed on one device, available through Libelium’s DIY hardware division, on the Cooking Hacks website. The e-Health sensor platform includes a spirometer, a pulse oximeter, sensors to measure blood pressure, temperature, body position, and it can monitor a number of biometric parameters.

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Patient Position Sensor - Accelerometer

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e-Health Sensor Shield over Arduino (left) and over Raspberry Pi (right)

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After receiving the e-Health Sensor Platform from Libelium, Script assembled a new system and began testing. Within days it became clear that input from more than one sensor would be needed. Script and his team started linking the other sensors’ inputs together, linking body position and heart rate to breath rate. Next, they added galvanic skin response to body position and temperature to breath rate. And, after developing various algorithms, the Inspire team found what they were looking for. They could accurately count breath rate.

Initial Requirements: from Prototype to Clinical Trials

The Inspire team integrated their sensor with the Libelium e-Health Sensor Platform to develop a more sophisticated diagnostic system for clinics and health professionals in developing countries. They brought the new device to a meeting in New York City of the largest NGOs. “As you would expect, most were mollified by our presentation. It was not to be believed”, said Script. After several clinical trials, visits to pediatricians and pulmonologists, more clinical research and a lot of focus “we are ready to assist health professionals deliver the breath of life”, he said.

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The INSPIRE device measures breath rate to diagnose pneumonia in infants: an early prototype

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Inspire Living’s initial requirements were to build a better diagnostic for children with pneumonia in developing countries for use by healthcare aides with no education or limited medical training.

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Demonstrating ease of use of INSPIRE in respiratory screening tests

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The INSPIRE device replaces the outdated methods used by health workers up to now. Currently, measuring breath rates involves nurses and doctors counting using a minute timer or even using beads, methods that are susceptible to errors and could cost a child the chance to receive medicine in time.

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Breath rate testing can be done on any child in any position, whether sitting or lying down

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The INSPIRE device measures patterns of breath recognition with an algorithm that analyses the data and displays the information to be easily read by non-skilled field personnel. The device tests breath rate in 15-second intervals and can conduct multiple tests within a one-minute time frame, permitting healthcare workers time to observe other signs of patient distress.

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Device evolution: from early prototype to current version

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With INSPIRE, the company has addressed many of the evolutions of the product during prototyping, and has now contracted with Project HOPE and other NGOs to take the units into the field and bring back the data they need to take the product to better developments. Clinical trials are ongoing. Results of the field trials will be available from June 2014.


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Source: Libelium

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